Searchable abstracts of presentations at key conferences in endocrinology

ea0003p216 | Reproduction | BES2002

Activation of supraoptic nucleus (SON) oxytocin neurones during mouse parturition

Douglas A , Willen S

Oxytocin drives parturition by contracting the uterus, but transgenic mice with no oxytocin appear to give birth normally. We have previously shown that oxytocin antagonist administration delays births showing that oxytocin plays a role in normal mouse parturition. Here, we tested the hypothesis that oxytocin neurones are active during parturition, using double immunocytochemistry for Fos and oxytocin to show neuronal activation and radioimmunoassay of blood samples to seek in...